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dalcetrapib Advisory Board Meeting
Pre-Meeting Survey
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1. DalCor is pursuing pharmacogenomic precision medicine hypothesis in cardiovascular disease with dalcetrapib and conducted research over the last 5 years.
1a. What is your level of enthusiasm about this hypothesis on a scale of 1 to 5 (where 5 is extremely enthusiastic)
*
1
2
3
4
5
1b. What are your reservations about this hypothesis?
*
2. In view of the 2018 and 2019 changes in the AHA/ACC and ESC/EAS guidelines respectively, what do you consider as the best post-ACS standard of care today?
*
3. Assuming a statistically significant dal-GenE study with at least 15% RRR on top of best standard of care:
3a. Would you perform a simple genetic blood test to determine the ADCY9 genotype of your ACS patients?
*
Yes
No
Maybe
3b. If an ACS patient has the ADCY9 AA genotype, would you treat him with dalcetrapib?
*
Yes
No
3c. What are the drivers for treating post-ACS patients with the ADCY9 AA genotype with dalcetrapib?
*
3d. What are the barriers for treating post-ACS patients with the ADCY9 AA genotype with dalcetrapib?
*
4. What is your expectation for a drug delivering at least 15% RRR on top of best standard of care being incorporated into the AHA/ACC and/or ESC/EAS guidelines?
*
5. What are the drivers for inclusion into the AHA/ACC and/or ESC/EAS guidelines?
*
6. What are the barriers to inclusion into the AHA/ACC and/or ESC/EAS guidelines?
*
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*
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