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dalcetrapib Advisory Board Meeting
Post-Meeting Survey
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1. Did the video on the scientific hypothesis of dalcetrapib as introduced by Prof. Chris Packard provide a clear and concise explanation of the proposed scientific hypothesis of dalcetrapib?
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Yes
No
If No, please propose the areas where you consider further explanation to be required:
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2. What is your overall feedback on the Scientific Hypothesis?
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3. Is there an alternative hypothesis that you would like to propose to explain the interaction of ADCY9, CETP and dalcetrapib?
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Yes
No
If Yes please provide details:
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4. Which Mechanism of Action (MoA) could also explain any potential benefit of dalcetrapib that may be observed in dal-GenE in 2021 (tick all that apply)
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a. lipid-modulating
b. anti-inflammatory
c. direct-anti-atherosclerotic
d. NO-mediated-effect
e. other
4e. If other please provide details:
5a. Assuming a positive dal-GenE study in 2021: How important on a scale of 1 to 5 (where 5 is extremely important) is it to have established a MoA to explain the positive results?
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1
2
3
4
5
5b. What evidence would you need to explain this hypothesis to your peers?
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5c. Considering other treatment options, where would you rank pharmacogenomic precision medicine with dalcetrapib in your post-ACS treatment strategies?
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Email Address
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